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PBPK Modeler


About PhinC Development

PhinC Development is the expert partner for small to medium sized pharmaceutical or biotech companies, who need to move forward in early drug research. Thanks to a multidisciplinary team with thorough field experience, PhinC Development helps to take the best decisions concerning drug development using all existing pharmacology and pharmacometrics modeling & simulation (M&S) tools (PBPK, PopPK, PKPD and simulations). Becoming part of our team will give you hands-on experience and the chance to:

  • Work in a dynamic environment
  • Be in a company in which innovation, people and entrepreneurship are the fundamentals of its success


Your Responsibilities include:

  • Develop and execute scientifically sound, innovative and business-oriented Modeling & Simulation (M&S) strategic plans for projects in various disease areas and different stages of product development, including regulatory submissions
  • Develop and execute appropriate PBPK models in the context of drug development
  • Conduct simulations to inform drug development decisions such as in vitro in vivo extrapolation, drug-drug interaction, formulation studies, simulations in special populations, dose regimen selection and other trial design features
  • Communicate the outcome of M&S analysis to sponsors to support efficient discussion and decision making
  • Contribute to responses to health authority requests and interactions to align on Clinical development and M&S strategy
  • Interact on a scientific level with sponsors with regards to all aspects of the application of M&S to ensure efficient and appropriate integration of M&S strategy and results into project.

Your profile

  • You either hold a PhD and/or a master’s degree in a relevant area (PBPK, pharmaceutical sciences or other related scientific discipline) and have already worked with PBPK modeling software such as GastroPlus, PK-sim or any other PBPK software. Knowledge in Phoenix WinNonLin, Monolix or NONMEM will be an asset.
  • You have at least 1 year of experience in PBPK modeling (mandatory).
  • You are fluent in English both orally and written, have good communication and presentation skills, scientific rigor and motivation.
  • You have a strong desire to further develop and apply modeling and simulation in drug development and appreciate working in teams of scientists with different backgrounds,

Job Type: Full-time Contract (permanent)

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